The star has given the entirety of his £25k Mercury Prize winnings to the trust for venues, which operates to preserve the United Kingdom's small live music spots.
The star was given the award on 16 October as his third album the album was declared the top album of the last 12 months.
The musician has chosen to donate the funds to the trust, in acknowledgment of the crucial part grassroots venues played in his early career.
"I personally couldn't be pursuing what I am doing today if it hadn't been for all the gigs I did around the North East, and elsewhere, when I was starting out," said Sam Fender. "These venues are renowned, but they are in difficulty."
Since the start of 2023, at least 150 of these venues have ceased operations – about one-sixth of the whole industry in the UK.
Recently, top acts such as Pulp, Coldplay, Katy Perry and Sheeran have all aided the Music Venues Trust in its attempts to keep the scene afloat, by including a modest fee to their ticket costs, which benefits independent venues.
Sam Fender also took part, collecting more than £100,000 on his recent tour to assist 38 local spots across the UK.
The money assisted venues that were confronting potential shutdown due to difficulties caused by floods, fire incidents and bereavements, as well as permit problems, court cases and sound issues.
Some locations received financial assistance in improving facilities and gear that positively impacted performers and audiences.
"The notion that money from performances in large arenas supports the independent spots, where it all starts for artists like me, is just sensible," Sam Fender has stated.
Fender is among several artists to give his award funds to good deeds.
In Pulp received the trophy in the mid-90s for their release their work, vocalist the singer stated that the group would contribute their winnings to the organization War Child.
That year, rapper and singer the artist divided her bounty across multiple organizations, including the NSPCC and a Sickle Cell charity.
"I also gave a thousand pounds to Highgate Newtown, to their classes, because I practiced gymnastics when I was a child and they lacked better apparatus," the artist told outlets.
Previously, Ezra Collective donated their funds to the local youth club that developed their group, in addition to other independent music bodies.
Also the 1994 recipients M People donated their prize to a MS organization after a friend was diagnosed the disease.
"Winning was quite enough," remarked singer the singer. "The cash was the cherry on top but we could do without the extra, because we had the honor. So our success touched another person's life."
Last week, the Music Venues Trust announced it had rescued two small stages in that region, by placing them under local control.
The Joiners in Southampton and the second in Bristol were acquired under the public acquisition scheme, which is funded by a national body and enthusiasts who purchase "shares" in the venues.